Cellular Energy
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Sep 10, 2025
From Tired to Wired: How NAD+ and MOTS-C Support Your Cellular Batteries
From Tired to Wired: How NAD+ and MOTS-C Support Your Cellular Batteries
Your Cellular Power Crisis
As we age, mitochondrial efficiency drops. NAD+ (a vital coenzyme) and MOTS-C (a mitochondrial-encoded peptide) approach cellular energy from different angles.
NAD+: The Universal Cellular Currency
Required in hundreds of enzymatic reactions
Supports ATP production, sirtuins, DNA repair, circadian rhythm
Declines markedly with age
MOTS-C: The Mitochondrial Messenger
Activates AMPK and metabolic adaptation pathways
Travels to the nucleus to influence gene expression
Improves metabolic flexibility and stress resilience
Better Together
NAD+ supplies substrate and signaling support
MOTS-C improves the “engine efficiency”
Together: fuel + optimization for cellular power
Handling & Quality
Protect NAD+ from light/heat; store properly
Ensure precise MOTS-C sequence and stability testing
99%+ purity and batch-specific COAs
Bottom line: Pairing NAD+ with MOTS-C supports both immediate energy needs and long-term mitochondrial performance.