Thymosin Alpha 1

Thymosin Alpha 1 (Tα1) is a naturally occurring peptide derived from prothymosin alpha, widely recognized for its critical role in modulating immune function. Tα1 enhances the activity of T-cells, particularly CD8+ cytotoxic T lymphocytes, which are crucial for adaptive immunity and pathogen clearance. It also stimulates natural killer (NK) cells, improves the function of antigen-presenting cells (APCs), and regulates the production of cytokines to balance pro-inflammatory and anti-inflammatory responses.

These actions make Tα1 a subject of interest in conditions related to immune suppression, chronic infections, and cancer. Additionally, its ability to counteract oxidative stress and support cellular repair processes has expanded its potential applications in aging and immunosenescence research. Tα1 is extensively studied for its therapeutic potential in infectious diseases, immune dysregulation, and chronic inflammation.