Tesamorelin

Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to produce and secrete endogenous growth hormone (GH). It acts by binding to GHRH receptors, triggering the release of GH, which in turn stimulates the production of insulin-like growth factor 1 (IGF-1), a key mediator of growth and metabolic processes.

Tesamorelin is distinct from other GH secretagogues due to its specific focus on increasing endogenous GH levels, which helps to preserve the natural pulsatile secretion of GH.Tesamorelin is primarily studied for its effects on reducing visceral fat, particularly in patients with conditions such as HIV-associated lipodystrophy, but its potential applications extend to general fat reduction and metabolic improvements.