Retatrutide

Retatrutide is a novel peptide that functions as a multi-receptor agonist, targeting the GLP-1, GIP, and glucagon receptors. This triple action sets it apart from other incretin-based therapies by enhancing glucose metabolism, reducing food intake, and promoting energy expenditure through a combination of hormonal pathways. GLP-1 receptor activation promotes insulin secretion and delays gastric emptying, while GIP receptor stimulation aids in glucose regulation. The glucagon receptor activation adds a unique thermogenic effect, potentially enhancing fat oxidation.

Retatrutide is being explored for its potential in addressing obesity and metabolic disorders by offering a multi-faceted approach to weight management and glucose control, combining the benefits of incretin mimetics with additional metabolic enhancements.