Kisspeptin-10
Kisspeptin is a neuropeptide hormone that serves as the master regulator of the reproductive axis, controlling GnRH release and coordinating the hypothalamic-pituitary-gonadal (HPG) cascade.
Kisspeptin activates KISS1R (GPR54) receptors on GnRH neurons, triggering pulsatile GnRH release that drives LH and FSH secretion, with studies showing 20-fold increases in LH within 30 minutes of administration.
Research demonstrates kisspeptin's critical role in puberty initiation, fertility regulation, and reproductive cyclicity, with deficiencies linked to hypogonadotropic hypogonadism and delayed puberty.
Studies reveal additional metabolic functions including glucose homeostasis regulation, with kisspeptin neurons integrating nutritional status with reproductive capacity through leptin and insulin signaling pathways.
Kisspeptin provides precise reproductive axis control, restored hormonal pulsatility, and metabolic-reproductive integration, offering researchers a fundamental tool for investigating neuroendocrine regulation and fertility optimization.
Composition: Kisspeptin-10 (5 mg)